Two cases of acute liver failure complicated by COVID-19 remarkably responded to anticoagulant therapy
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- Oobo Hiromitsu
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Inada Hiroki
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Setoyama Hiroko
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Narahara Satoshi
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Tanaka Kentaro
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Kurano Soutaro
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Tokunaga Takayuki
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Iio Etsuko
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Yoshimaru Yoko
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Nagaoka Katsuya
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Watanabe Takehisa
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Tanaka Motohiko
- Public Health and Welfare Bureau, City of Kumamoto
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- Tateyama Masakuni
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
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- Tanaka Yasuhito
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
Bibliographic Information
- Other Title
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- 抗凝固療法が著効したCOVID-19合併急性肝不全の2例
- コウギョウコ リョウホウ ガ チョコウシタ COVID-19 ガッペイ キュウセイ カンフゼン ノ 2レイ
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Abstract
<p>Case 1 was an 83-year-old man. After testing positive for SARS-CoV-2 at a previous hospital, he was transferred to our hospital due to a rapid increase in liver enzymes. Although he had acute liver failure with coagulation abnormalities, when subcutaneous injection of unfractionated heparin was initiated, liver failure and coagulation abnormalities promptly improved. Case 2 was a 29-year-old man. After testing positive for SARS-CoV-2 in a previous hospital, a rapid increase in liver enzymes with coagulation abnormalities was observed. On day 6 of illness, he fell into a coma and was transferred to our hospital with a diagnosis of acute liver and renal failure. The initiation of artificial liver support therapy with unfractionated heparin improved his level of consciousness and liver failure. We report two rare cases in which coagulopathy and liver failure due to COVID-19 infection rapidly improved with intensive medical care, including early anticoagulant therapy.</p>
Journal
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- Kanzo
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Kanzo 64 (6), 270-279, 2023-06-01
The Japan Society of Hepatology
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Details 詳細情報について
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- CRID
- 1390014901285285120
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- NII Book ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL BIB ID
- 032867300
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
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- Abstract License Flag
- Disallowed
