ENDOSCOPIC DIAGNOSIS OF ALCOHOL-RELATED UPPER GASTROINTESTINAL DISEASES

DOI
  • SASAKI Fumisato
    Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences.
  • KANMURA Shuji
    Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences.
  • IDO Akio
    Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences.

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  • アルコール多飲者の上部消化管疾患に対する内視鏡診断―食道扁平上皮癌・下咽頭癌を中心に―

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<p>Alcohol-related upper gastrointestinal diseases encompass a spectrum of conditions, prominently including esophageal squamous cell carcinoma, alongside head and neck cancers such as hypopharyngeal cancer, and gastric cancer. Notably, esophageal squamous cell carcinoma exhibits a strong association with the ethanol content in alcohol and the aldehydes generated during alcohol metabolism. To identify patients at high risk for alcohol-related upper gastrointestinal diseases, it is important to utilize alcohol-related questionnaires and genetic polymorphism association tests targeting alcohol metabolism enzymes. Furthermore, image-enhanced endoscopy is useful for diagnosing hypopharyngeal and esophageal squamous cell carcinomas. Early diagnosis of alcohol-related upper gastrointestinal diseases requires performing endoscopic observations tailored to the patientʼs risk level.</p>

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