二価金属存在下におけるクエン酸第二鉄錯体とＤｅｓｆｅｒｒｉｏｘａｍｉｎｅ　Ｂのリガンド交換動力学

DOI

書誌事項

タイトル別名
  • Ligand-Exchange Kinetics of Fe(III)-Citrte Complex with Desferrioxamine B in the Presence of Divalent Metals

抄録

We have developed a kinetic model for ligand-exchange reaction of ferric iron-citrate complex (FeCit) with desferrioxamine B (DFB) in the presence of divalent metals (Ca and Mg). The kinetic model considers (1) a disjunctive pathway where DFB binds to Fe following the dissociation of FeCit and (2) an adjunctive pathway where FeDFB is formed via the direct association of DFB to FeCit. The rate constants for the complex reaction in the disjunctive pathway estimated from the model well described the experimentally determined rate constants. In the adjunctive pathway, the reaction rate was found to be affected by the concentrations of divalent cations and citrate. The kinetic data in the adjunctive pathway was well explained by involving the effect of direct association of divalent cation to the precursor complex. The results indicated the significant effect of divalent cations on the kinetics for the ligandexchange of iron-citrate complex with DFB.

収録刊行物

キーワード

詳細情報 詳細情報について

  • CRID
    1390282679088056704
  • NII論文ID
    130003775876
  • DOI
    10.11532/proes1992.44.115
  • ISSN
    1884829X
    13415115
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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