New Cineromycins and Musacins Obtained by Metabolite Pattern Analysis of Streptomyces griseoviridis FH-S 1832). II. Structure Elucidation.

DOI PubMed 2 Citations

Bibliographic Information

Other Title
  • II. Structure Elucidation

Search this article

Description

A detailed analysis of the secondary metabolite pattern produced by Streptomyces griseoviridis (strain FH-S 1832) using a chemical screening method resulted in the detection, isolation and structure elucidation of new 14-membered lactones of the cineromycin B-type [dehydrocineromycin B (5), oxycineromycin B (7), and 2, 3-dihydrocineromycin B (8)], as well as new γ-lactones related to nigrosporalactone and 4, 5-dihydroxy-octa-2, 6-dienoic acid esters named musacins A to F (10, 13-15, 17, 18 and 21). The constitution of these metabolites were deduced from spectroscopic data as well as chemical transformations. The configuration of musacin D (10) was determined by derivatization with chiral acids (Helmchen's method).

Journal

Citations (2)*help

See more

Details 詳細情報について

  • CRID
    1390282679127602304
  • NII Article ID
    130003503100
  • DOI
    10.7164/antibiotics.49.438
  • COI
    1:CAS:528:DyaK28Xjt1Gktbo%3D
  • ISSN
    18811469
    00218820
    http://id.crossref.org/issn/00218820
  • PubMed
    8682720
  • Text Lang
    en
  • Article Type
    journal article
  • Data Source
    • JaLC
    • Crossref
    • PubMed
    • CiNii Articles
  • Abstract License Flag
    Disallowed

Report a problem

Back to top