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- SCHLEGEL ROLF
- Deutsche Akademie der Wissenschaften zu Berlin, Zentralinstitut für Mikrobiologie und Experimentelle Therapie
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- THRUM HEINZ
- Deutsche Akademie der Wissenschaften zu Berlin, Zentralinstitut für Mikrobiologie und Experimentelle Therapie
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説明
The polyene antibiotic flavomycoin contains a pentaene chromophore which is conjugated with the lactone carbonyl group. This fact was proved by reduction of flavomycoin with lithium aluminum hydride, by low temperature ultraviolet spectroscopy and the infrared absorption of perhydro-flavomycoin. Oxidative degradation of perhydro-flavomycoin resulted in 2-methyl-tridecane-1, 13-dioic acid which was identified by gas chromatography and mass spectrometry. A partial formula for flavomycoin is given.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 24 (6), 368-374, 1971
公益財団法人 日本感染症医薬品協会
