A Reductive Acidolysis Final Deprotection Strategy in Solid Phase Peptide Synthesis Based on Safety-Catch Protection.
書誌事項
- タイトル別名
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- Reductive Acidolysis Final Deprotection
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説明
A reductive acidolysis final deprotection strategy in solid phase peptide synthesis was developed using a new safety-catch type of semi-permanent protecting groups and new linkers which were derived from 4-methylsulfinylbenzyl protection. This new strategy was based on a two-dimensional protection scheme employing acid-labile temporary and acid-stable but reductive acidolysis-cleavable semi-permanent protecting groups. By using this strategy, we successfully synthesized four model peptides, of which two contained C-terminal amide.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 45 (1), 18-26, 1997
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679137445888
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- NII論文ID
- 130003947146
- 110003616362
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 4121808
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- PubMed
- 9023966
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可