Synthesis of Some New Spiropyranoquinolines and Evaluation of Their Free Radical Scavenging Activity
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- Panteleon Vassiliki
- Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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- Kostakis Ioannis K.
- Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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- Marakos Panagiotis
- Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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- Pouli Nicole
- Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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- Andreadou Ioanna
- Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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説明
The preparation of some new spiro-substituted 4-hydroxypyranoquinolinones and their corresponding dihydropyrano cis-diols is described. The free radical scavenging activity of the compounds was determined by means of their interaction with the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) and the superoxide anions generated by the enzymic xanthine–xanthine oxidase system. The spiroadamatylpyranoquinolinone analogue proved to be the most efficient free radical scavenger.
収録刊行物
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- ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ
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ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ 57 (5), 446-452, 2009
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679146679168
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- NII論文ID
- 130000124554
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 10213011
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- 抄録ライセンスフラグ
- 使用不可