Synthesis of Spiro [4-hydroxycyclohexane-1, 4'-2', 3'-dihydro-6'-methoxy-2'-methyl-1'H-isoquinoline]
Search this article
Description
For the purpose of testing the biological activity, spiro [4-hydroxycyclohexane-1, 4'-2', 3'-dihydro-6'-methoxy-2'-methyl-1'H-isoquinoline] (III) was synthesized by a sequence of reactions including the Schmidt reaction on the indanone (XIV). The compound (III) was found to have a considerably lower anti-cholinesterase activity than galanthamine (I).
Journal
-
- Chemical and Pharmaceutical Bulletin
-
Chemical and Pharmaceutical Bulletin 17 (8), 1564-1568, 1969
The Pharmaceutical Society of Japan
- Tweet
Details 詳細情報について
-
- CRID
- 1390282679149248768
-
- NII Article ID
- 110003621064
-
- NII Book ID
- AA00602100
-
- ISSN
- 13475223
- 00092363
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed