Pathogenesis of Hypertension in Rabbits with Coarctation of the Abdominal Aorta

  • Fujii Jun
    Institute for Adult Diseases, Asahi Life Foundation
  • Murata Kazuhiko
    The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
  • Yamaguchi Hiroshi
    The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
  • Kuramochi Morio
    The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
  • Seki Akira
    The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
  • Ikeda Masao
    The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo

この論文をさがす

抄録

Abdominal aorta of the rabbit was constricted with a silver clip above or below the renal arteries. A persistent rise of blood pressure was observed only in rabbits with aortic constriction above the renal arteries. The hypertension did not develop in rabbits with aortic constriction below the renal arteries. Plasma renin activity was within normal limits in 8 rabbits at acute stage of hypertension and was suppressed in 8 rabbits with chronic hypertension. The results indicate that the hypertension following aortic constriction is renal in origin and some renal mechanism not associated with renin-angiotensin system may be involved in it.

収録刊行物

詳細情報 詳細情報について

問題の指摘

ページトップへ