書誌事項
- タイトル別名
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- Immunological action of Neurotropin. (5). Effect of Neurotropin on immuno-suppression caused by stress.
- Neurotropin ノ メンエキ ヤクリガクテキ サヨウ 5 ストレス フ
- Effect of Neurotropin on immunosuppression caused by stress
- ―ストレス負荷による免疫機能の低下に対する作用―
この論文をさがす
説明
Neurotropin is an extract isolated from the inflamed skins of rabbits inoculated with Vaccinia virus. A study was carried out to examine the effect of Neurotropin on the immunosuppressions caused by stress. Mice were restrained for 16 hr per day for 2 consecutive days. Under this condition, the immune responses such as PFC and DTH to SRBC, T cell-dependent antigen, were markedly suppressed. Moreover, the phagocytic activity of macrophages were also suppressed. Neurotropin was found to restore such suppressions of both T cell response and phagocytosis in stressed mice. These results suggest that the effect of Neurotropin on depressed immunity in stressed mice were not only restoration of T cell function but also phagocytic activity of macrophages. Neurotropin had no effect on intact immune responses without stress. This suggests that Neurotropin can he used as an effective immunomodulator.
収録刊行物
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- 日本薬理学雑誌
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日本薬理学雑誌 90 (1), 67-71, 1987
公益社団法人 日本薬理学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282679250518016
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- NII論文ID
- 130000759454
- 30034985675
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- NII書誌ID
- AN00198335
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- COI
- 1:CAS:528:DyaL2sXlsleqsbo%3D
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- ISSN
- 13478397
- 00155691
- http://id.crossref.org/issn/00155691
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- NDL書誌ID
- 3137272
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- PubMed
- 3653803
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可