A Case of Facial Atypical Candidasis in a Patient with Advanced Colorectal Carcinoma during the Treatment with Cetuximab

DOI Web Site 3 References

Bibliographic Information

Other Title
  • セツキシマブ治療中患者に発症した顔面非定型皮膚カンジダ症の１例
  • 症例 セツキシマブ治療中患者に発症した顔面非定型皮膚カンジダ症の1例
  • ショウレイ セツキシマブ チリョウ チュウ カンジャ ニ ハッショウ シタ ガンメン ヒテイケイ ヒフ カンジダショウ ノ 1レイ

Search this article

Abstract

A 55-year old female patient with advanced colorectal carcinoma was referred to us, for the treatment of cutaneous toxicity induced by cetuximab. Although typical acneiform eruptions appeared on her face after second treatment with cetuximab, the treatment was stopped after fourth administration because of rapid exacerbation of these eruptions. On admission to our hospital, she showed facial eruptions similar to those observed in dermatitis with impetiginization, Candida albicans was however revealed by microscopic and culture studies. Therefore, her facial complications were diagnosed as atypical cutaneous candidiasis that was induced under immunosuppressive condition secondary to cetuximabtreatment and topical steroid application. Although cutaneous toxicity was promptly improved by the application of a topical anti-fungal cream, colorectal carcinoma was remarkably worsened. Adverse reactions induced by cetuximab treatment are well-known; however, some patients show unexpected reactions secondary to cetuximabtreatment. Therefore, dermatologists play an important role in ensuring that the quality of life (QOL) of patients is improved during the course of cancer treatment, particularly by careful inspection of the alteration of skin manifestations and an early recognition of unexpected cutaneous toxicities.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 73 (3), 245-247, 2011

    Western Division of Japanese Dermatological Association

References(3)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top