プロプラノロールが有効であった巨大な乳児血管腫の 1 例

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  • A Case of Giant Infantile Hemangioma Successfully Treated with Propranolol
  • ショウレイ プロプラノロール ガ ユウコウ デ アッタ キョダイ ナ ニュウジ ケッカン シュ ノ 1レイ

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A 10-month-old girl presented with an erythema on the left side of her face, present since 1 month of age. Despite previous treatments with dye laser surgery and intralesional injection of corticosteroids, the lesion had gradually protruded into an erythematous bulky mass with a deformity of the left auricle and difficulty in opening her left eyelid. She was diagnosed as infantile hemangioma (IH) and started on a treatment with propranolol. Propranolol was initiated at a dose of 0.25 mg/kg per day and titrated upward to 1.0 mg/kg per day. The hemangioma began to withdraw within a week, and afterward, the mass decreased without any side effects. A first line treatment of IH with a giant mass or functional disorder is currently the administration of oral or intralesional corticosteroids, but that may not be effective in some cases. Recently, the efficacy of propranolol for IH has been reported in many cases. Propranolol may be tried for the treatment of IH for extensive periods of time with an adequate monitoring of adverse effects.

収録刊行物

  • 西日本皮膚科

    西日本皮膚科 74 (4), 394-398, 2012

    日本皮膚科学会西部支部

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