THE DIFFERENCE BETWEEN GROSS TUMOR VOLUME AND BIOLOGICAL TARGET VOLUME IN POSTOPERATIVE LOCAL RECURRENT RECTAL CANCER; A PRELIMINARY STUDY OF PET/CT RADIATION THERAPY PLANNING

DOI 15 References
  • JINGU Keiichi
    Department of Radiation Oncology, Tohoku University School of Medicine
  • TAKEDA Ken
    Department of Radiation Oncology, Tohoku University School of Medicine
  • METOKI Takahiro
    Department of Radiation Oncology, Tohoku University School of Medicine
  • OGAWA Yoshihiro
    Department of Radiation Oncology, Tohoku University School of Medicine
  • ARIGA Hisanori
    Department of Radiation Oncology, Tohoku University School of Medicine
  • YAMADA Shogo
    Department of Radiation Oncology, Tohoku University School of Medicine
  • TAKAI Yoshihiro
    Course of Health Sciences, Tohoku University School of Medicine
  • HOSOGAI Yoshiyuki
    Course of Health Sciences, Tohoku University School of Medicine
  • KANEDA Tomohiro
    Department of Diagnostic Radiology, Tohoku University School of Medicine
  • MITSUYA Masatoshi
    Department of Radiology, Tohoku University Hospital
  • WATANABE Satoru
    Department of Radiology, Tohoku University Hospital

Bibliographic Information

Other Title
  • 直腸癌術後再発に対するPET/CT planningに関する初期研究～GTVとBTVの相違～

Search this article

Description

Purpose: To reveal the difference of gross tumor volume (GTV) in CT with biological target volume (BTV) in positron emission tomography using 18F-fluorodeoxyglucose with computed tomography (FDG-PET/CT).<br>Materials and Methods: In 7 patients with postoperative local recurrence rectal cancer, three independent radiation oncologists delineated target volume on CT and PET, respectively, and compared the volume of GTV with that of BTV using the two-factor repeated measures ANOVA. FDG-PET/CT was performed in the same position as radiotherapy. The images by CT and PET were sent to the radiation therapy planning system as the DICOM datum, respectively, and fused those images using DICOM information. Each radiation oncologist delineated the abnormal shadow on CT as GTV and delineated macroscopically the region with high FDG accumulation using the tumor/muscle ratio.<br>Results: In those seven patients, mean GTV was 77.2±53.6 cm3 and mean BTV was 58.0±48.0 cm3, and BTV was statistically smaller than GTV (p<0.001). There was a strong correlation between GTV and BTV (r=0.952, p<0.001). In patients with local recurrent rectal cancer, there were no significant differences among radiation oncologists (F (2, 18)=0.654, MSe=5220.046, p=0.532).<br>Conclusion: There was a significant difference between the target volume on functional image (PET/CT) and the target volume on morphologic image (CT) in the patients with local recurrent rectal cancer.

Journal

  • The Journal of JASTRO

    The Journal of JASTRO 20 (3), 127-131, 2008

    Japanese Society for Therapeutic Radiology and Oncology

References(15)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top