Pacritaxel for the treatment of a patient with angiosarcoma of the scalp

  • HIOKI Kana
    Department of Dermatology, Gifu University School of Medicine
  • IZUMI Tomoko
    Department of Dermatology, Gifu University School of Medicine
  • NAGAI Miki
    Department of Dermatology, Gifu University School of Medicine
  • KAMIYA Hideki
    Department of Dermatology, Gifu University School of Medicine
  • KITAJIMA Yasuo
    Department of Dermatology, Gifu University School of Medicine

Bibliographic Information

Other Title
  • パクリタキセルが有効であった頭部血管肉腫の1例

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Description

We reported a case of angiosarcoma in a 68-year-old man. The patient had noticed some subcutaneous nodules on the left side of his forehead during the previous two years. Although, he was treated first with radiotherapy and IL-2 therapy, metastasis to the left cervical lymph node and the lungs were developed one year later. For the treatment of the metastasis, we performed intravenous Pacritaxel injection concurrent with radiation and local injection of IL-2. Pacritaxel 55mg/m2 was administrated 3 times at six-day intervals. After 2 courses of this therapy, metastasis of lung resions had disappeared, leaving the side effect of leukopenia. After two courses of this treatment, we have continued the chemotherapy with a smaller dosage. Unfortunately, at the present time of 20 months after his first visit, metastasis to the abdominal wall was revealed and an aggravation tendency could not be prevented, although, the primary lesion had been kept in good condition without erosion or nodules. Pacritaxel should be recommended as an alternative treatment for angiosarcoma of the scalp. [Skin Cancer (Japan) 2004; 19: 107-111]

Journal

  • Skin Cancer

    Skin Cancer 19 (1), 107-111, 2004

    The Japanese Skin Cancer Society

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