A Case of Giant Brunner’s Gland Hyperplasia in the Duodenum

  • Matsumoto Yasunori
    Department of Frontier Surgery, Chiba University Graduate School of Medicine
  • Natsume Toshiyuki
    Department of Frontier Surgery, Chiba University Graduate School of Medicine
  • Akai Takashi
    Department of Frontier Surgery, Chiba University Graduate School of Medicine
  • Kawahira Hiroshi
    Department of Frontier Surgery, Chiba University Graduate School of Medicine Research Center for Frontier Medical Engineering, Chiba University
  • Hayashi Hideki
    Department of Frontier Surgery, Chiba University Graduate School of Medicine Research Center for Frontier Medical Engineering, Chiba University
  • Matsubara Hisahiro
    Department of Frontier Surgery, Chiba University Graduate School of Medicine

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Other Title
  • 巨大な十二指腸Brunner腺過形成の1切除例

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A 54-year-old male admitted to the hospital because of black stool and high grade anemia was found to have a huge neoplasm in the bulb of his duodenum using a gastroendoscope. Abdominal CT and MRI scans revealed a neoplasm about 5cm in diameter. It was difficult to grasp the whole image of the tumor by the gastroendoscopy and to resect the large tumor via gastroendoscopy. Therefore, the tumor was extirpated under laparotomy with intraoperative gastroendoscopy. The tumor was 6.5×2.5×2.0cm with Brunnerʼs gland hyperplasia, which had a stalk on the duodenal bulb. The patientʼs postoperative course was uneventful. There is an increasing number of reports of tumors arising from Brunnerʼs gland, but the diagnosis and treatment of these tumors is still unclear. We analyzed the pertinent literature regarding Brunnerʼs gland hyperplasia, hamartoma, adenoma, and carcinoma.

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