A case of peribronchiolar metaplasia difficult to differentiate from early-stage lung adenocarcinoma because of increasing part-solid nodule

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  • Matsui Shinji
    Division of General Thoracic Surgery, Tottori University Hospital
  • Araki Kunio
    Division of General Thoracic Surgery, Tottori University Hospital
  • Matsuoka Yuki
    Division of General Thoracic Surgery, Tottori University Hospital
  • Miwa Ken
    Division of General Thoracic Surgery, Tottori University Hospital
  • Taniguchi Yuji
    Division of General Thoracic Surgery, Tottori University Hospital
  • Nakamura Hiroshige
    Division of General Thoracic Surgery, Tottori University Hospital

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  • 緩徐に増大するpart-solid noduleを呈し，早期肺腺癌との鑑別が困難であったperibronchiolar metaplasiaの1例

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The patient was a 70-year-old male. After surgery for esophageal cancer, a 7-mm pure ground glass nodule appeared in the left lower lobe of the lung. After four years, a solid component appeared in the center of the GGN, and the nodule increased slowly to 11 mm. We suspected lung adenocarcinoma and performed partial resection by thoracoscopic surgery. Histopathologically, columnar ciliated cells or cuboidal cells lined the alveolar walls, and the cells had mild atypia with metaplasia. From these findings, it was diagnosed as peribronchiolar metaplasia (PBM). Since PBM has exhibited such CT findings, the differentiation between PBM and early-stage lung adenocarcinoma was thought to be important.

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