Using Linkage Map of Mouse for Prediction of Gene Location in Animals

  • Wada Yasuhiko
    Department of Animal Breeding and Genetics, National Institute of Animal Industry
  • Kishino Hirohisa
    Laboratory of Biometrics, graduate school of Agricultural and Life Sciences, University of Tokyo
  • Kashiwagi Nobuhisa
    The Instiute of Statistical Mathematics

Bibliographic Information

Other Title
  • マウスゲノムとの比較遺伝子地図を用いた末マッピング遺伝子の染色体の予測

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Description

The high-density linkage map of mouse has been constructed. This map contains quantitative trait loci (QTL) and major genes which are not mapped on other animals. In this study, a Bayesian model was developed to predict the chromosome number of unmapped genes in animals using comparative mapping data in contrast with mouse linkage map. The comparative mapping data of mouse-human, mouse-rat and mouse-cattle is collected from the Animal Genome Database. In order to examinethe accuracy of our method, we randomly divided the data into two subsets. The ratios of chromosomal translocation of mouse-human, mouse-rat and mouse-cattle were estimated by one of the subsets, and the chromosome numbers of mapped genes of human, rat and cattle were predicted for another subset.

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Details 詳細情報について

  • CRID
    1390282679346451072
  • NII Article ID
    130002151922
  • DOI
    10.5691/jjb.20.193
  • ISSN
    21856494
    09184430
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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