グルコースにて作動する減圧機構と化学駆動・制御による人工すい臓モデルに関するレビュー

DOI Web Site Web Site 参考文献10件

書誌事項

タイトル別名
  • Review of Glucose-Driven Decompression Device for a Chemical Controlled Artificial Pancreas
  • グルコース ニテ サドウ スル ゲンアツ キコウ ト カガク クドウ ・ セイギョ ニ ヨル ジンコウ スイゾウ モデル ニ カンスル レビュー

この論文をさがす

抄録

Glucose-driven decompression device which utilizes conversion of chemical energy (glucose) to mechanical energy (actual pressure) has been developed and applied for a novel chemical controlled artificial pancreas system. The artificial system does not need to require any other power source such as electrical or mechanical energy. Integrated intermittent drug release actions and pressure changes were observed in record with CCD camera. The system was then evaluated in closed loop system setting for feedback control of the glucose concentration. The data revealed that drug release interval was extended causing stabilized constant glucose concentration on feedback effect. Accordingly, glucose concentration can be controlled autonomously similar with natural pattern of interdependent relationship between pancreas insulin secretion and glucose level. Potential applications of the organic engine include intelligent actuators, DDS (drug delivery system) and artificial muscles using biological energies (sugar, acid, lipid, etc.) with a neglibly-small heat loss.

収録刊行物

参考文献 (10)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ