Histopathological Examination of Spontaneous Lesions in Amami Rabbits (<I>Pentalagus furnessi</I>): a Preliminary Study Using Formalin-Fixed Archival Specimens

DOI 3 Citations 11 References
  • KUBO Masahito
    Laboratory of Veterinary Pathology, Joint Faculty of Veterinary Medicine, Yamaguchi University
  • NAKASHIMA Tomomi
    Laboratory of Veterinary Pathology, Joint Faculty of Veterinary Medicine, Yamaguchi University
  • HONDA Takuma
    Laboratory of Veterinary Pathology, Joint Faculty of Veterinary Medicine, Yamaguchi University
  • KOCHI Yoshie
    Amami Wildlife Conservation Center, Ministry of the Environment
  • ITO Yui
    Amami Wildlife Conservation Center, Ministry of the Environment
  • HATTORI Shosaku
    Amami Laboratory of Injurious Animals, The Institute of Medical Science, The University of Tokyo
  • KURAISHI Takeshi
    Amami Laboratory of Injurious Animals, The Institute of Medical Science, The University of Tokyo

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Other Title
  • アマミノクロウサギ（<I>Pentalagus furnessi</I>）における自然発生病変の病理組織学的検索：ホルマリン保存臓器を用いた予備的研究
  • Histopathological Examination of Spontaneous Lesions in Amami Rabbits (Pentalagus furnessi): a Preliminary Study Using Formalin-Fixed Archival Specimens

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Formalin-fixed archival specimens of 131 free-ranging Amami rabbits (Pentalagus furnessi) collected between August 2003 and March 2012 were histopathologically examined. Systemic protozoal infection (probably toxoplasmosis) was diagnosed in an adult female rabbit, and purulent bronchopneumonia due to Gram-negative bacilli infection and fibrinous pericarditis were observed in a young male rabbit. Additionally, various findings such as accumulations of foamy macrophages (suspected endogenous lipid pneumonia), focal fungal pneumonia, focal pyogranulomatous pneumonia, pulmonary abscess, and renal abscess, were found. Among these findings, accumulations of foamy macrophages were most frequently observed (43 of 113 cases). The present study revealed various spontaneous lesions in free-ranging Amami rabbits; however, the results seemed to be limited. Construction of the monitoring system regarding pathological status of all dead Amami rabbits will be needed.

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