コントロールリリース基剤としての微粉化低置換度ヒドロキシプロピルセルロース（Ｌ‐ＨＰＣ）の湿式造粒による徐放性能変化

DOI オープンアクセス

書誌事項

タイトル別名
  • Changes in Controlled-release Functions of Pulverized Low-substituted Hydroxypropylcellulose by Wet Granulation.
公開日
1992
DOI
  • 10.4164/sptj.29.456
公開者
一般社団法人 粉体工学会

この論文をさがす

説明

Pulverized L-HPC (low-substituted hydroxypropylcellulose, LH41) is used as a controlled-release matrix filler, depending on the amount of loading in its formulation. The flowability and packability of the L-HPC particles in drugs were facilitated by wet granulation to improve their availabilities for practical uses. Controlled-release functions of the L-HPC were reserved through granulation with ethanol, whereas they were lost during granulation with water. The differences in the controlled release functions of agglomerated L-HPC were explained in terms of their swelling properties, depending on the type of slovent used for the granulation.

収録刊行物

  • 粉体工学会誌

    粉体工学会誌 29 (6), 456-459, 1992

    一般社団法人 粉体工学会

キーワード

詳細情報 詳細情報について

  • CRID
    1390282679487765504
  • NII論文ID
    130003952052
  • DOI
    10.4164/sptj.29.456
  • ISSN
    18837239
    03866157
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
    • OpenAIRE
  • 抄録ライセンスフラグ
    使用不可

問題の指摘

ページトップへ