書誌事項
- タイトル別名
-
- Dry Surface Modification of Adhesive Fine Particle by a Horizontal Shear Mixer with Super High Speed Chopper
- チョウコウソク チョッパー オ ユウスル スイヘイガタ カクハン コンゴウキ オ モチイタ フチャクセイ ビリュウシ ノ カンシキ ヒョウメン カイシツ
この論文をさがす
抄録
Improvement of flowability and dissolution property of particles was conducted by a dry surface modification using a novel shear mixer with a super high speed chopper (SPM mixer). Corn starch and ibuprofen were treated with silica under various rotation speeds and operation time. The flowability was evaluated by an angle of repose and dissolution property was evaluated by a dissolution test according to the Japanese Pharmacopoeia. <br>It was found that composite particles with good flowability were obtained within 1 minute treatment time. And it was implied that the faster rotation speed of chopper resulted in the shorter treatment time.<br>In the SPM mixer, surface modification and grinding were progressed simultaneously. Within 1 minute treat time, the particle size was smaller and dissolution velocity was faster by an increase of rotation speed of chopper. And composite particles with superior flowability obtained.
収録刊行物
-
- 粉体工学会誌
-
粉体工学会誌 50 (6), 410-415, 2013
一般社団法人 粉体工学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679489835904
-
- NII論文ID
- 10031178139
-
- NII書誌ID
- AN00222757
-
- COI
- 1:CAS:528:DC%2BC3sXht1ChtrbE
-
- ISSN
- 18837239
- 03866157
-
- NDL書誌ID
- 024692320
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可