Adding isosorbide to some beverages may improve the drug compliance

DOI 1 Citations
  • KUBO Kazuhiko
    Department of Otorhinolaryngology, Kyushu University Hospital
  • SATO Masanobu
    Department of Otorhinolaryngology, Kyushu University Hospital
  • KOMUNE Shizuo
    Department of Otorhinolaryngology, Kyushu University Hospital

Bibliographic Information

Other Title
  • イソバイド服薬改善テストの結果報告

Search this article

Description

Isosorbide is one of drugs used for the treatment of patients with Meniere's disease, but there is often poor compliance due to its bitter taste. We recruited healthy volunteers to test whether isosorbide could be made more palatable by adding it to a beverage. The subjects frequently complained of a bitter taste when they took isosorbide alone. They documented that there was a significantly improved taste when they took isosorbide by adding it to orange juice, coca-cola oran ion-tonic beverage. However, they tended to document that there was an even worse taste when they took isosorbide after adding it to green tea. These results indicate that adding isosorbide to orange juice, coca-cola or an ion-tonic beverage may improve drug compliance.

Journal

  • jibi to rinsho

    jibi to rinsho 59 (3), 122-127, 2013-05-20

    JIBI TO RINSHO KAI

Citations (1)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top