THE DIRECT EFFECT OF 860 nm LIGHT ON CELL PROLIFERATION AND ON SUCCINIC DEHYDROGENASE ACTIVITY OF HUMAN FIBROBLASTS INVITRO
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- Bolton Peter
- <i>Tissue Repair Research Unit, Division of Anatomy and Cell Biology, United Medical and Dental Schools of Guy’s and St. Thomas’s Hospitals, Guy’s Hospital Campus</i>
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- Young Steve
- <i>Tissue Repair Research Unit, Division of Anatomy and Cell Biology, United Medical and Dental Schools of Guy’s and St. Thomas’s Hospitals, Guy’s Hospital Campus</i>
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- Dyson Mary
- <i>Tissue Repair Research Unit, Division of Anatomy and Cell Biology, United Medical and Dental Schools of Guy’s and St. Thomas’s Hospitals, Guy’s Hospital Campus</i>
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説明
Human forearm fibroblasts were irradiated, in vitro, using a Microlaser Medical Pen Unit (Johnson and Johnson) with a wavelength of 860 nm, and an average power output of 50 mW. The irradiation distance and times were adjusted to give energy densities of 2 J/cm2 and 16 J/cm2 respectively. The control unit was adjusted to give a continuous waveform. Fibroblast proliferation and succinic dehydrogenase activity were assessed every 24 hrs over a five day period. The results obtained suggest a relationship between fibroblast proliferation and succinic dehydrogenase activity. At the lower energy density (2 J/cm2), succinic dehydrogenase levels rise with fibroblast proliferation. However, at an energy density of 16 J/cm2, the succinic dehydrogenase levels and fibroblast proliferation appear to be inhibited. These findings agree with previously reported data.
収録刊行物
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- レーザーセラピー
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レーザーセラピー 7 (2), 55-60, 1995
国際光治療学会
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詳細情報 詳細情報について
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- CRID
- 1390282679608531840
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- NII論文ID
- 130004872720
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- ISSN
- 18847269
- 08985901
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可