- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Automatic Translation feature is available on CiNii Labs
- Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
A case of thalamic hemorrhage which occurred during anticoagulant therapy with Xa inhibitor and expanded even after the administration of prothrombin complex concentrate
-
- Hamada Hiroyuki
- Department of Cerebrovascular Medicine and Neurology, National Hospital Organization Kyushu Medical Center
-
- Wada Shinichi
- Department of Cerebrovascular Medicine and Neurology, National Hospital Organization Kyushu Medical Center
-
- Mima Yohei
- Department of Cerebrovascular Medicine and Neurology, National Hospital Organization Kyushu Medical Center
-
- Yasaka Masahiro
- Department of Cerebrovascular Medicine and Neurology, National Hospital Organization Kyushu Medical Center
-
- Kuwashiro Takahiro
- Department of Cerebrovascular Medicine and Neurology, National Hospital Organization Kyushu Medical Center
-
- Okada Yasushi
- Department of Cerebrovascular Medicine and Neurology, National Hospital Organization Kyushu Medical Center
Bibliographic Information
- Other Title
-
- Xa 阻害薬による抗凝固療法中に視床出血を発症し，第IX 因子複合体製剤投与後も血腫増大を呈した1 症例
Search this article
Description
An 82-year-old man treated with rivaroxaban 10 mgQD for prevention of stroke associated with nonvalvular atrial fibrillation developed left thalamic hemorrhage with symptoms of consciousness disturbance and right hemiparesis and was transferred to our hospital after about 2 hours and 3 hours of taking tablet, respectively. Head computed tomography (CT) examination demonstrated the left thalamic hemorrhage with size of 10 ml. Immediately, administration of antihypertensive agents was started to keep systolic blood pressure below 140 mmHg and 1,000 IU of prothrombin complex concentrate (PCC) was administered which reversed prothrombin time-international normalized ratio (PT-INR) from 1.33 to 1.14. However, the size of hematoma grew up to be 21 ml and 23 ml after 3 hours and 5 hours after the admission, respectively. It seems that lowering blood pressure and administration of PCC may be ineffective against hematoma expansion in brain hemorrhage occurring within a couple of hours after taking rivaroxaban.
Journal
-
- Japanese Journal of Stroke
-
Japanese Journal of Stroke 38 (6), 413-417, 2016
The Japan Stroke Society
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282679615881728
-
- NII Article ID
- 130005284877
-
- ISSN
- 18831923
- 09120726
-
- Text Lang
- ja
-
- Article Type
- journal article
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
- KAKEN
-
- Abstract License Flag
- Disallowed
