臨床応用されているDDS  ホルモン製剤のDDS  (LH‐RHアゴニストの徐放性製剤)

書誌事項

タイトル別名
  • Drug delivery system in hormonal agents: long-term release LH-RH agonist
  • Drug delivery system in hormonal agents : long-term release LH-RH agonist
  • ホルモン製剤のDDS(LH-RHアゴニストの徐放性製剤)

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抄録

Leuprorelin (leuprolide) acetate, a highly active agonist of luteinizing hormone-releasing hormone (LH-RH) has been widely accepted as a representative agent utilizing drug delivery system. A single injection of this one-month or three-month depot provides persistent drug release, which has been applied to therapy in patients with prostate cancer, breast cancer, endometriosis, myoma uteri, and central precocious puberty. The profile of this drug from basic research to clinical application was reviewed.

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