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- 堂坂 弘俊
- 北海道大学医学部第1内科
書誌事項
- タイトル別名
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- The induction of sister chromatid exchanges by benzo(a)pyrene in cultured peripheral blood lymphocytes from lung cancer patients and from healthy individuals with high or low risks of cancer.
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抄録
The inducibility of sister chromatid exchanges (SCEs) by benzo [a] pyrene (BP) was studied in cultured peripheral blood lymphocytes of untreated lung cancer patients and healthy individuals with high or low risk for developing cancer, each of the 3 groups consisting of 15, 11, 14 subjects, respectively. We defined those who had 4 or more family members with malignant neoplasia within the third-degree relatives as members of the high risk group, while those who had no such familial history of neoplasia were defined as members of the low risk group. The lung cancer patients came from neither group. The spontaneous SCE frequency in lymphocytes of lung cancer patients was signifcantly higher than that of low risk individuals. The SCE yeilds by BP in the lymphocytes from lung cancer patients and members of the high risk group were significantly greater than members of the low risk group. The present findings suggest that members of high risk group may be more susceptible to BP than members of low risk group.
収録刊行物
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- 肺癌
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肺癌 26 (7), 737-743, 1986
特定非営利活動法人 日本肺癌学会
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詳細情報 詳細情報について
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- CRID
- 1390282679654448128
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- NII論文ID
- 110003131114
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- NII書誌ID
- AN00203978
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- ISSN
- 13489992
- 03869628
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可