辺縁性歯周炎の免疫病理学的研究　ＶＩＩ　　歯周炎と細菌酵素　２　　炎症歯肉におけるＢａｃｔｅｒｉａｌ　ｃｈｏｎｄｒｏｉｔｉｎａｓｅ　ＡＢＣとＨｙａｌｕｒｏｎｉｄａｓｅについて

DOI

書誌事項

タイトル別名
  • Immunopathological study of periodontal disease Localization of bacterial chondroitinase ABC and hyaluronidase in the gingiva of individuals with periodontal disease.
  • Localization of bacterial chondroitinase ABC and hyaluronidase in the gingiva of individuals with periodontal disease
  • 第7報歯周炎と細菌酵素 (その2) 炎症歯肉におけるbacterial chondroitinase ABCとhyaluronidaseについて

抄録

The purpose of this investigation was to study the presence of bacteria chondroitinase ABC and basterial hyaluronidase in inflamed human gingiva by a fluorescence antibody technique. The presence of chondroitinase ABC was demonstrated in all of 30 cases and hyaluronidase was detected in 21 cases. Both enzymes existed on the surface of gingival epithelium, in the epithelium, in the subepithelial connective tissue and in the cytoplasm of phagocytes. The existence was mainly in the sulcular portion. The tissue or cells in which the enzymes localized suffered from destruction such as degenera-tive, atrophic and/or necrotic changes, and widened intercellluar spaces were also observed in the sulcular epithelium.<BR>From the above results, it was indicated that chondroitinase ABC and hyaluronidase, produced in dental plaque, penetrated from the surface of gnigival epithelium by hydrolysing acid mucopolysacchalide in the space of epithelium to supepithelial connective tissue and initiated periodontal disease.

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詳細情報 詳細情報について

  • CRID
    1390282679659055104
  • NII論文ID
    130004001190
  • DOI
    10.2330/joralbiosci1965.25.437
  • ISSN
    03850137
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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