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Clinicopathologic Study of Surgically Treated Cases of Tracheobronchial Adenoid Cystic Carcinoma
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- Shimizu Junzo
- Department of Surgery, KKR Hokuriku Hospital
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- Oda Makoto
- Department of Chest Surgery, Kanazawa University School of Medicine
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- Matsumoto Isao
- Department of Chest Surgery, Kanazawa University School of Medicine
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- Arano Yoshihiko
- Department of Surgery, KKR Hokuriku Hospital
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- Ishikawa Norihiko
- Department of Surgery, KKR Hokuriku Hospital
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- Saitoh Kenichiro
- Department of Surgery, KKR Hokuriku Hospital
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- Minato Hiroshi
- Department of Clinical Pathology, Kanazawa Medical University
Bibliographic Information
- Other Title
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- 気管・気管支に発生した腺様嚢胞癌切除例の臨床病理学的検討
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Description
Objective. We conducted a clinicopathologic study of surgically treated cases of tracheobronchial adenoid cystic carcinoma (ACC). Materials and Methods. Of the 1,909 patients with lung cancer who underwent resection in our hospital and associated institutes during the 28-year period between 1980 and 2007, five (0.3%) were pathologically diagnosed as ACC of the trachea, bronchus and lung. All 5 patients were women aged from 37 to 67 years, with an average age of 50.8 years. Four tumors were located in the larger airways (one in the carina, one in the right main bronchus, one in the left main bronchus, one in the middle lobe bronchus) and one tumor was located in the peripheral lung of left S4b. The following operations were done: bronchoplastic procedures in 3 (carinal resection with double-barreled carinoplasty in 1, sleeve right pneumonectomy in 1, sleeve middle lobectomy in 1), left pneumonectomy in 1, and left upper lobectomy in 1. Results. Three of 5 patients have survived for 172, 144, and 10 months after surgery, respectively, but 2 of the patients died 15 and 95 months after surgery, respectively (The cause of death of one patient was distant metastases to the skin, breast, and lung, and that of the other patient was colon cancer). Conclusion. For local treatment for ACC of the major airway, the best method is considered to be sleeve resection of the trachea or bronchus in an area where airway reconstruction may not be disturbed and to add postoperative irradiation when there is residual carcinoma at the stump. However, it seems controversial to recommend adjuvant radiotherapy in all patients undergoing resection.<br>
Journal
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- Haigan
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Haigan 48 (4), 261-265, 2008
The Japan Lung Cancer Society
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Keywords
Details 詳細情報について
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- CRID
- 1390282679659187968
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- NII Article ID
- 110006985829
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- NII Book ID
- AN00203978
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- ISSN
- 13489992
- 03869628
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- HANDLE
- 2297/20404
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- Text Lang
- ja
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- Article Type
- journal article
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- Data Source
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- JaLC
- IRDB
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed