Ａｎａｐｌａｓｔｉｃ　ｌａｒｇｅ　ｃｅｌｌ　ｌｙｍｐｈｏｍａと結節硬化型Ｈｏｄｇｋｉｎ病の２例　リンパ節腫よう細胞像の比較

DOI

書誌事項

タイトル別名
  • Two cases of anaplastic large cell lymphoma and nodular sclerosis type Hodgkin's disease - A comparison in cytologic features of tumor cells in lymph nodes.
  • A comparison in cytologic features of tumor cells in lymph nodes
  • リンパ節腫瘍細胞像の比較

抄録

Background: We treated 2 cases of anaplastic large cell lymphoma (ALCL) and nodular sclerosis Hodgkin's disease (NS-HD). It remains difficult to differentiate ALCL from NS-HD histopathologically without immunohistochemical techniques. We compared the cytological features of tumor cells in lymph nodes from patients using imprint cytology.<BR>Results: The following differences were found between the 2 diseases: 1) Tumor cells mutually adhered to form a mass in ALCL, whereas lacunar cells were diffuse and inflammatory cells, such as small lymphocytes, occurred in the background in NS-HD, 2) In ALCL, tumor cells were large but relatively even in site, whereas lacunar cells in NS-HD were larger and sizes varied markedly, 3) Nuclear polymorphism and hyperchromatism were more pronounced in lacunar cells. 4) In ALCL, Reed-Sternberg (RS)-like cells were observed to have 2 nuclei, whereas Hodgkin cells and RS cells in NS-HD were larger and accompanied by a perinucleolar halo, 5) Large numbers of tumor cells having a typical doughnut-shaped nucleus were detected in ALCL but hardly any in NS-HD.<BR>Conclusions: The above differences may provide valuable cytological information in the differential diagnosis of ALCL and NS-HD.

収録刊行物

キーワード

詳細情報 詳細情報について

  • CRID
    1390282679667259776
  • NII論文ID
    130003758834
  • DOI
    10.5795/jjscc.40.144
  • ISSN
    18827233
    03871193
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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