Myoepithelial carcinoma of the breast—A case report—

DOI 19 References
  • URANO Makoto
    Department of Diagnostic Pathology, Fujita Health University, School of Medicine
  • FUJIWARA Maki
    Department of Pathology, Fujita Health University Hospital
  • TANAKA Kouichi
    Department of Pathology, Fujita Health University Hospital
  • ITOH Satomi
    Department of Pathology, Fujita Health University Hospital
  • HIRASAWA Yutaka
    Department of Pathology, Fujita Health University Hospital
  • KIRIYAMA Yuka
    Department of Diagnostic Pathology, Fujita Health University, School of Medicine
  • MIZOGUCHI Yoshikazu
    Department of Diagnostic Pathology, Fujita Health University, School of Medicine
  • KURODA Makoto
    Department of Diagnostic Pathology, Fujita Health University, School of Medicine

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Other Title
  • 乳腺筋上皮癌の 1 例
  • Myoepithelial carcinoma of the breast^|^mdash;A case report^|^mdash;

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Background : Myoepithelial tumor of the breast is rare, and its cytological finding in not well established. We report a case of myoepithelial carcinoma of the breast.<br>Case : A 71-year-old female noticed a mass in the right breast. Ultrasonography revealed a solid tumor, 1.5 cm in diameter. Fine needle aspiration (FNA) cytology specimens showed cohesive epithelial cell clusters and fascicular spindle cells accompanying numerous myxoid matrix which demonstrated metachromasia in Giemsa stain. Histologically, the tumor composed of spindle to polygonal cell proliferation with myxoid matrix and dense fibrosis. The tumor cells expressed several myoepithelial cell markers and showed “triple negative” pattern in immunohistochemistry.<br>Conclusion : It is important to recognize the various cell shape and cell arrangement of neoplastic myoepithelial cells in making accurate cytological diagnosis of myoepithelial lesions. Giemsa stain is useful to recognize stromal myxoid matrix which may indicate it myoepithelial cell origin.

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