Stage III,IV口腔癌に対する浅側頭動脈よりの超選択的動注法を用いた術前放射線化学療法

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タイトル別名
  • PREOPERATIVE CHEMORADIOTHERAPY USING SUPERSELECTIVE INTRAARTERIAL INFUSION VIA SUPERFICIAL TEMPORAL ARTERY FOR STAGE III, IV ORAL CANCER

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Thirty-eight patients with stage III, IV oral cancer were treated by preoperative chemoradiotherapy using superselective intraarterial infusion via the superficial temporal artery. Radiotherapy (total dose: 40Gy) and chemotherapy using CBDCA (total dose: 460mg/m2) were performed daily, followed by surgery. Catheter-insertion of 34 patients was done successfully. Four catheter insertions were not done successfully because of the anomaly of the artery such as common trunk of the lingual artery and the facial artery. The clinical effects were CR in 9 patients (26.5%) and PR in 25 (73.5%), and histopathological effects after surgery were grade III, IV in 10 (29.4%), grade IIb in 23 (67.6%), and grade IIa in 2 (5.8%). The 5-year cumulative survival rate was 67.8%. This superselective intra arterial infusion method could be the technique of choice for the treatment of oral cancer.

収録刊行物

  • 頭頸部腫瘍

    頭頸部腫瘍 28 (1), 253-258, 2002

    日本頭頸部癌学会

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