歯周炎治療用DDSの臨床評価  文献による比較検討

  • 千葉 智子
    北海道医療大学歯学部附属病院薬剤部
  • 阪田 久美子
    北海道医療大学歯学部附属病院薬剤部 北海道医療大学薬学部臨床薬剤学教室
  • 小川 隆志
    北海道医療大学歯学部附属病院薬剤部
  • 宮崎 正三
    北海道医療大学薬学部臨床薬剤学教室

書誌事項

タイトル別名
  • Clinical evaluation of DDS for periodontitis. A comparative literature study.
  • —A comparative literature study—
  • ―文献による比較検討―
公開日
2000
DOI
  • 10.11263/jsotp1982.19.85
公開者
日本歯科薬物療法学会

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説明

As drug information service (DI) in a dental hospital, we evaluated the efficacy and safety of three products of the drug delivery system (DDS) (Periocline®, Elyzole®, Perio Chip®) for treatment of periodontitis, using literature of clinical trials.<BR>Nine literature references (4 for Periocline®, 4 for Elyzole®, 1 for Perio Chip®) were obtained from a MEDLINE database search on the Internet.<BR>The clinical trial design of each reference was a randomized control trial, and three were double blind randomized control trials. The treatment period and examination period were different for each reference. Items of clinical examination included pocket depth (PD), bleeding on probing (BOP), attachment level (AL), plaque index (PI) ; of these, PD was used in all trials.<BR>As for the efficacy of products evaluated by improvement of PD, two references for Periocline®, and one for Periochnp®, showed statistically significant improvement, but two references for Elyzole®, indicated superior improvement of PD in the control group rather than the test group. Only five of the references discussed side effects, but they were mild, transit, local effects.

収録刊行物

  • 歯科薬物療法

    歯科薬物療法 19 (2), 85-94, 2000

    日本歯科薬物療法学会

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