しん出性中耳炎とＩＡＰ，ＩＳ　ＩＩＩ　　マクロファージに及ぼすＩＳの影響

DOI

書誌事項

タイトル別名
  • Immunosuppressive acidic protein and immunosuppressive substance in middle ear effusion. (Third report). Response of macrophage to IS.
  • Response of Macrophage to IS
  • マクロファージに及ぼすISの影響

説明

It was reported that the IS levels in serous middle ear effusion were significantly high and rat IS certainly prolongated the histological inflammation of rat middle ear with OME induced by formalin-killed H. influenzae. In order to reveal the real mechanism of the histological changes, the response of macrophage to IS was examined. The effect of IS on the phagocytic activity of macrophage was not significant, however the PGE2 production of macrophage by IS treatment was considerable. These results suggest that PGE2 induced by macrophage is one of the factors of prolongation of histological inflammation of OME which is caused by formalin-killed H. influenzae.

収録刊行物

詳細情報 詳細情報について

  • CRID
    1390282679747217792
  • NII論文ID
    130004355843
  • DOI
    10.11289/otoljpn1981.19.310
  • ISSN
    18845797
    02889781
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

問題の指摘

ページトップへ