胎盤移行したバルプロ酸の新生児期における消失半減期(1例報告)
書誌事項
- タイトル別名
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- A case of the elimination half-life of valproic acid in a newborn infant.
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The pharmacokinetic parameters of valproic acid (VPA) transferred via the placenta were clinically investigated in a newborn infant born to an epileptic mother. The newborn, delivered at about 37-week gestation, was a healthy male (birth weight 2, 500g). The Apgar score was 6. The serum levels of VPA between 6 hours and 8 days after birth were monitored by the FPIA method. The elimination pattern was mono-exponential, and the pharmacokinetic parameters were t 1/ 2= 45.7 hr and Kel= 0.0152 hr-1 according to the one compartment model.
収録刊行物
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- 病院薬学
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病院薬学 12 (4), 313-315, 1986
一般社団法人 日本医療薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679751983488
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- NII論文ID
- 110001798236
- 130004298976
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- NII書誌ID
- AN00002794
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- ISSN
- 21859477
- 03899098
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- NDL-Digital
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可