書誌事項
- タイトル別名
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- Effect of exogenous mouse interferon on murine fulminant hepatitis induced by Mouse Hepatitis Virus (MHV)-2
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抄録
We investigated the effect of exogenous mouse interferon produced by L-cell on the growth of MHV-2 in the liver tissue, the progression of liver cell necrosis, and the subsequent survival time in murine fulminant hepatitis induced by MHV-2. Murine fulminant hepatitis was made in 4-week-old male ICR (SPF) mice by the intraperitoneal inoculation of MHV-2 (105/PFU/mouse). Mouse interferon (103/IU/Mouse/day) was intraperitoneally injected every day. MHV-2 in the liver tissue was plaque assayed using DBT-cell after homogenization of the liver tissue. Exogenous mouse interferon suppressed both the growth of MHV-2 in the liver tissue and the progression of liver cell necrosis, and also prolonged survival time. Regarding survival time, the earlier the injection of mouse interferon was started, the longer survival time was increased.
収録刊行物
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- 肝臓
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肝臓 25 (1), 18-23, 1984
一般社団法人 日本肝臓学会
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詳細情報 詳細情報について
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- CRID
- 1390282679769080320
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- NII論文ID
- 130000874695
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- ISSN
- 18813593
- 04514203
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可