肝障害時のlipoprotein-X出現の意義に関する研究

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書誌事項

タイトル別名
  • Studies on clinical significance of lipoprotein-X in the liver diseases
  • カン ショウガイジ ノ lipoprotein X シュツゲン ノ イギ ニカ
  • (I) Appearance of an abnormal lipoprotein in rats with experimental cholestasis
  • (I) 実験肝障害と異常リポ蛋白

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抄録

This study was carried out with D-galactosamine administrated rats and bile duct ligated rats, in order to throw some lights on the relationship between appearance of abnormal lipoprotein (Ab-Lp) and liver function. By the changes of liver function and histological findings, both animals showed liver injury with cholestasis. Then, Ab-Lp was detected in the sera of both animals by Bacto-agar electrophoresis. Electrophoretic patterns of these Ab-Lp seemed to be the same with rat lipoprotein-X which was reported by some investigators. As the conclusion, the appearance of Ab-Lp in the blood is closely related to cholestatic condition of the liver. However, the direct evidence of the mechanism of Ab-Lp formation is still remained unclear.

収録刊行物

  • 肝臓

    肝臓 19 (1), 43-51, 1978

    一般社団法人　日本肝臓学会

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