急性肝炎におけるinsulin-glucagon療法の効果

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タイトル別名
  • Insulin-glucagon therapy on acute hepatitis
  • キュウセイ カンエン ニ オケル insulin glucagon リョウホウ

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抄録

In order to evaluate the effect of insulin-glucagon (I-G) therapy on acute hepatitis, the present study was carried out on 2 cases of fulminant hepatitis (FH), 3 cases of subacute hepatitis (SH) and 8 cases of acute hepatitis (AH). These cases were treated with 10% glucose fluid (500ml) containing regular insulin (10 units) and glucagon (1mg). Normotest (NT), prothrombin time (PT), α2-HS-glycoprotein and prealbumin were measured. In FH and SH, the mean values of NT remained less than 10%. In AH the mean values of NT increased after I-G therapy, but these values were decreased when I-G therapy was stopped. In FH and SH, PT remained prolonged and in AH, it was slightly shortened during I-G therapy. In FH and SH, the mean values of α2-HS-glycoprotein remained less than 20mg/dl. In AH, the mean values were increased after I-G therapy. In FH and SH, the mean values of prealbumin were less than 5mg/dl. In AH, they increased, but these values were decreased when I-G therapy was stopped. From these results we suggest that I-G therapy may enhance the reserve of liver in acute hepatitis.

収録刊行物

  • 肝臓

    肝臓 21 (12), 1626-1630, 1980

    一般社団法人　日本肝臓学会

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