肝疾患における血清LDH zymogramの検討

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書誌事項

タイトル別名
  • Studies on Serum Lactic Dehydrogenase Isoenzyme in Hepatic Diseases
  • カン シッカン ニ オケル ケッセイ LDH zymogram ノ ケントウ

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説明

LDH zymograms of sera from patients with hepatic disorders were studied by using a technique of agar-gel electrophoresis. Elevated activities of LDH5 were frequently observed in various liver diseases. In acute hepatitis, LDH5 activities still elevated even after the serum total LDH activities returned to the normal level in the recovery stage. In primary hepatoma, activities of LDH5 showed a tendency to be higher than those of LDH4. On the other hand, in metastatic liver cancer activities of LDH3 as well as LDH4 were increased distinctly, and activities of LDH4 appeared to be higher than those of LDH5. Therefore, the differences of the zymographic patterns of LDH between primary and metastatic liver cancer seemed to be useful for differentiating the both types of liver cancer.

収録刊行物

  • 肝臓

    肝臓 16 (9), 587-596, 1975

    一般社団法人　日本肝臓学会

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