色素沈着症におけるパンテテイン‐Ｓ‐スルホン酸Ｃａ塩の安全性と有用性

DOI

書誌事項

タイトル別名
  • Safety and Clinical Study of Calcium Pantetheine-S-Sulfonate in Patients with Hyperpigmentation

抄録

Calcium Pantetheine-S-Sulfonate (PaSSO3Ca) is one of the pantothenic acid derivatives.<BR>We examined PaSSO3Ca inhibition capacity ofmelanin formation in vitro. For the safetyevaluation, we tested PaSSO3Ca cream to thefifty one patients with skin diseases by closedpatch method. And clinical evaluation ofPaSSO3Ca was performed in the fifty patientswith hyperpigmentation by half side method.Results were as follows<BR>1. We showed PaSSO3Ca inhibition capacityof melanin formation in vitro.<BR>2. PaSSO3Ca cream was shown to be safetyto the human skin.<BR>3. 10% PaSSO3Ca cream lightened the skin hyperpigmentation more than placebo cream.

収録刊行物

  • 皮膚

    皮膚 26 (1), 162-174, 1984

    日本皮膚科学会大阪地方会

キーワード

詳細情報 詳細情報について

  • CRID
    1390282679777207040
  • NII論文ID
    130003843250
  • DOI
    10.11340/skinresearch1959.26.162
  • ISSN
    1884541X
    00181390
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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