メチルプレドニゾロンの強大音受傷性に与える影響
書誌事項
- タイトル別名
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- Effect of Methylprednisolone upon Susceptibility to Acoustic Trauma.
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説明
To investigate the effect of steroid upon acoustic trauma, 32 albino guinea pigs were given 12 or 40mg/kg methylprednisolone (mPSL) i.v. and exposed to 2kHz pure tone of 110 or 120 dBSPL for 10min. The threshold of the compound action potential (CAP) were examined before and every 30min after the exposure to intense sound. The CAP threshold shift by acoustic overstimulation in these mPSL pretreated animals was not significantly different from that in the control animals. However, some mPSL given animals exhibited significant recovery in the CAP threshold during the observation period of 3 hours, while the threshold shift was quite minimal in the control. These results indicate that mPSL dose not exert in a protective manner but has presumably some effects on the recovery from the damage induced by acoustic overstimulation.
収録刊行物
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- ＡＵＤＩＯＬＯＧＹ ＪＡＰＡＮ
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ＡＵＤＩＯＬＯＧＹ ＪＡＰＡＮ 37 (4), 288-294, 1994
一般社団法人 日本聴覚医学会
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詳細情報 詳細情報について
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- CRID
- 1390282679816817920
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- NII論文ID
- 130003862301
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- ISSN
- 18837301
- 03038106
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可
