Serum Paraoxonase Activity and Genotype Distribution in Japanese Patients with Diabetes Mellitus.
-
- SAKAI Takenori
- The Third Department of Internal Medicine, Ehime University School of Medicine
-
- MATSUURA Bunzou
- The Third Department of Internal Medicine, Ehime University School of Medicine
-
- ONJI Morikazu
- The Third Department of Internal Medicine, Ehime University School of Medicine
書誌事項
- タイトル別名
-
- Serum Paraoxonase Activity and Genotype
この論文をさがす
抄録
We investigated the serum paraoxonase (PON) activity and genotype distribution in 139 patients with non-insulin-dependent diabetes mellitus and in 240 control subjects in a Japanese population. There were no significant differences in PON genotype frequencies between the diabetic and control subjects, but the PON activity was significantly less in diabetic subjects (p<0.01). PON activity was significantly related to levels of total cholesterol and high density lipoprotein (HDL) cholesterol in the control subjects, but not in the diabetic subjects. In diabetic subjects with the genotype A A, the mean maximum intimal-medial thickness (IMT) of the carotid artery was significantly greater than in subjects with genotype AB or BB. PON may play an important role in the development of atherosclerosis associated with diabetes mellitus.<br>(Internal Medicine 37: 581-584, 1998)
収録刊行物
-
- Internal Medicine
-
Internal Medicine 37 (7), 581-584, 1998
一般社団法人 日本内科学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282679843812224
-
- NII論文ID
- 10009507222
-
- NII書誌ID
- AA10827774
-
- COI
- 1:STN:280:DyaK1cznsFOjsw%3D%3D
-
- ISSN
- 13497235
- 09182918
-
- NDL書誌ID
- 4539436
-
- PubMed
- 9711883
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可