書誌事項
- タイトル別名
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- Ninjinyouei-to (TJ-108), a Chinese Medicine Containing Polygalae Radix, Increases the Blood Concentration of 1,5-anhydro-D-glucitol Independent of That of Glucose and HbA1C in Diabetic Patients.
- オンジ オ オオク フクム カンポウヤク(ニンジンヨウエイ ユ)ノ ケッセイ 1,5 アンヒドログルシトール(1,5AG)アタイ ニ オヨボス エイキョウ : ケンジョウジン オヨビ トウニョウビョウ カンジャ デ ノ ケントウ
- 健常人および糖尿病患者での検討
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抄録
The blood concentration of 1, 5-anhydro-D-glucitol (1, 5-AG) has been used asa marker for diabetic control. In diabetic patients, high urine glucose competes the absorption of1, 5-AG at renal tubules and lowers its blood concentration. In general, the major source of 1, 5-AG is food and daily in take was reported to be relatively stable in Japan. Although Chinese medicines have been traditionally and widely used for many kinds of disease, it is less known well that one of their components, especially polygalae radix, contains large amounts of 1, 5-AG. We examined the effect of an extract of polygalae radix and ninjinyouei-to (TJ-108) on the blood concentration of 1, 5-AG in 5 healthy volunteers and 13 patients including those with diabetes mellitus.We found that both the extract of polygalae radix and TJ-108 increase 1, 5-AG without affecting glucose metabolism.Chinese medicines containing polygalae radix should thus be better evaluated in 1, 5-AG blood concentration as a marker of diabetic control.
収録刊行物
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- 糖尿病
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糖尿病 45 (8), 583-587, 2002
一般社団法人 日本糖尿病学会
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詳細情報 詳細情報について
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- CRID
- 1390282679880710656
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- NII論文ID
- 40019915801
- 130004338859
- 10010940075
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- NII書誌ID
- AN00166576
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- ISSN
- 1881588X
- 0021437X
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- NDL書誌ID
- 025094721
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可