アフリカ風土病型カポシ肉腫

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タイトル別名
  • African endemic-type Kaposi's sarcoma. A histopathologic study and flow cytometric DNA analysis of nine cases.
  • アフリカ風土病型カポシ肉腫--9例における病理組織学的検診ならびにフローサイトメトリー法による核DNA量解析〔英文〕
  • アフリカ フウド ビョウケイ カポシ ニクシュ 9レイ ニ オケル ビョウリ
  • A HISTOPATHOLOGIC STUDY AND FLOW CYTOMETRIC DNA ANALYSIS OF NINE CASES

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説明

Flow cytometric DNA analysis using formalin-fixed, paraffin-embedded tissues were performed on nine cases of African endemic-type Kaposi's sarcoma (KS). Histologically, these cases were classified into the following three types; granulation tissuelike (one case), angioma/angiosarcoma-like (four cases) and spindle cell (four cases). Although these three types showed a variety of cellularity and cellular atypism, there were no fundamental differences in the view point of proliferation of spindle cell. Mitotic figures were not prominent. All cases were exclusively diploid and lacked an aneuploid population by flow cytometric measurement of DNA content. These results suggest that African endemic-type KS is a less aggressive disease rather than a malignant neoplasm.

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