エチレン―酢酸ビニル共重合体の

DOI

書誌事項

タイトル別名
  • Feasibility of ethylene-vinyl acetate copolymers as biomedical material.
  • 医用高分子材料としての可能性について
公開日
1975
DOI
  • 10.11392/jsao1972.4.14
公開者
一般社団法人 日本人工臓器学会

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説明

As part of the work to develop safer soft polymeric materials for medical use ethylene-vinyl acetate copolymers (EVA) were evaluated by physico-chemical and biological tests. Test materials were extracted in distilled water at 37°, 70° or 100°C. The extracts obtained were submitted to determining the amount of potassium permanganate-reducing substance, and the absorbance of ultraviolet absorption at 220mμ. Hemolytic activity was studied in two ways by exposing canine red blood cell to plastic surface, and to the extract that was prepared by extraction of test material in physiological saline solution. EVA showed very low level of teachable ingredients and hemolysis compared with Tygon. Antithrombogenicity of EVA was similar to that of silicone rubber. EVA was implanted subcutaneously in a dog for one year. Tensile strength and infrared absorption spectrum of the implanted film were practically unchanged. These results suggest that EVA is feasible as a safer soft material in biomedical applications.

収録刊行物

  • 人工臓器

    人工臓器 4 (1), 14-18, 1975

    一般社団法人 日本人工臓器学会

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