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EFFECT OF FLUTICASONE PROPIONATE AT HALF DOSE OF BECLOMETHASONE DIPROPIONATE DIVIDED TWICE DAILY AND ONCE DAILY IN ASTHMATICS INHALING BECLOMETHASONE DIPROPTONATE 800 μg DAILY OR MORE
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- Hasegawa Tsuyoshi
- Department of Pulmonary Medicine, Kobe City General Hospital
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- Tomii Keisuke
- Dept. of Respiratory Medicine, Tenri Hospital
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- Kikumoto Naoki
- Dept. of Internal Medicine, Tottori Seikyo Hospital
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- Sakamoto Hiroko
- Dept. of Internal Medicine Nishikobe Medical Center
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- Maekawa Toyoyuki
- Dept. of Internal Medicine, Hirashima Hospital
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- Katayama Satoru
- Dept. of Internal Medicine, Yohka Hospital
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- Kamei Tadashi
- Kagawa Prefectual Central Hospital
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- Sakamoto Yukihiro
- Anan Kyoei Hospital
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- Fujii Hiroshi
- Kobe City Nishi Shimin Hospital
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- Ishihara Kyohsuke
- Kobe City Nishi Shimin Hospital
Bibliographic Information
- Other Title
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- 高用量ベクロメタゾン吸入中の喘息症例における1/2用量フルチカゾン1日2回, および1日1回投与の有用性
- コウヨウリョウ ベクロメタゾン キュウニュウ チュウ ノ ゼンソク ショウレイ ニ オケル 1/2 ヨウリョウ フルチカゾン 1ニチ 2カイ,オヨビ 1ニチ 1カイ トウヨ ノ ユウヨウセイ
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Description
We conducted a 12 weeks single-arm prospective study comparing beclomethasone dipropionate (BDP), 1/2 doses of fluticasone propionate (FP) twice daily and the same dose of FP once daily in 47 asthmatics who had been inhalinn BDP 800 mcg daily or more. Peak expiratory flow (PEF) , FEV_1, a symptom score and a frectuency of β_2 agonist were all significantly better in FP twice daily phase than BDP phase (329 vs. 306 L/min, 1.87 vs. 1.76 L, 3.6 vs. 6.0/week and 2.7 vs. 4.5 puffs/day, respectively). There was no significant difference in these endpoints between FP twice daily phase and FP once daily phase. FP twice daily produced better plumonary function and symptom releif than the double doses of BDP. Furthermore, FP twice daily could, at least in a short-term basis, safely be changed into the same doses of FP once daily.
Journal
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- Japanese Journal of Allergology
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Japanese Journal of Allergology 50 (4), 379-384, 2001
Japanese Society of Allergology
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Keywords
Details 詳細情報について
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- CRID
- 1390282679960536448
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- NII Article ID
- 110002427031
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- NII Book ID
- AN00012583
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- ISSN
- 13477935
- 00214884
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- NDL BIB ID
- 026086467
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL Search
- CiNii Articles
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- Abstract License Flag
- Disallowed