-
- 小西 和朗
- 新潟大学医学部耳鼻咽喉科学教室
書誌事項
- タイトル別名
-
- IN VITRO ANTI-TUMOR ACTIVITY OF HUMAN BLOOD MONOCYTES AGAINST CULTURED HUMAN CANCER CELLS
- ヒト バイヨウ ガン サイボウ ニ タイスル タンキュウ ノ コウ シュヨウセ
この論文をさがす
抄録
Anti-tumor activity of the human blood monocytes against cultured human cancer cells was examined in vitro. The cell lines used in this study were Okajima (a stomach cancer), KatoIII (a stomach cancer) and Hattori (a breast cancer).<br>The anti-tumor activity of the monocytes from healty volunteers was not detected by 51Crrelease assay of the target tumor cells, but was demonstrated by 3H-thymidine incorporation test. This suggested that the anti-tumor activity was attributed to the cytostatic action. The inhibition of the growth of the tumor cells was observed irrespective of their origin. The growth of human normal fibroblasts was not inhibited by the activity of the monocytes.<br>The anti-tumor activity was enhanced by in vitro treatment of monocytes with immunopotentiaters, such as Propionibacterium acnes (P. acnes), P. acnes-cell wall skeleton (CWS), a streptococcal preparation (OK-432) and Nocardia-rubra-CWS. The activity was not enhanced by protein bound polysaccharide Kureha (PSK).<br>The activity of the monocytes from human umbilical cord blood was almost same to that of peripheral blood monocytes from healthy volunteers. The antitumor activity of peripheral blood monocytes from patients with head and neck cancer was also almost same to that of monocytes from healthy volunteers and was enhanced by the treatment with those immunopotentiaters in vitro.
収録刊行物
-
- 日本耳鼻咽喉科学会会報
-
日本耳鼻咽喉科学会会報 85 (2), 107-121, 1982
一般社団法人 日本耳鼻咽喉科頭頸部外科学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282679983995520
-
- NII論文ID
- 130000810052
-
- NII書誌ID
- AN00191551
-
- ISSN
- 18830854
- 00306622
-
- NDL書誌ID
- 2483397
-
- PubMed
- 7086563
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可