書誌事項
- タイトル別名
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- Two cases of hypersensitivity pneumonitis due to isocyanate in foundry castworkers.
- 公開日
- 1987
- 資源種別
- journal article
- DOI
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- 10.11389/jjrs1963.25.924
- 公開者
- 社団法人 日本呼吸器学会
この論文をさがす
説明
We reported two cases of hypersensitivity pneumonitis induced by the inhalation of isocyanate (MDI). The patients were 49 and 42 year-old males. They were engaged in casting at the same foundry and were dealing with MDI for two months, when dry cough, fever and exertional dyspnea developed. These symptoms improved while they took leave. Fine crackles were auscultated in both lungs at the inspiratory phase, and restricted pulmonary dysfunction with hypoxemia was noticed. Chest X-ray film revealed diffuse fine granular shadows on both lungs. Alveolitis, epithelioid granulomas and Masson's bodies were demonstrated in transbronchial lung biopsy specimens. Because of positive skin test, positive lymphocyte stimulation test and doubtful precipitation test utilizing isocyanate-human serum albumins, type IV allergy mechanism (Gell-Coombs) might have a significant role in the pathogenesis of this hypersensitivity pneumonitis induced by isocyanate.
収録刊行物
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- 日本胸部疾患学会雑誌
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日本胸部疾患学会雑誌 25 (8), 924-928, 1987
社団法人 日本呼吸器学会
