Association of location of deep venous thrombosis and d-dimer value in acute intracerebral hemorrhage

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  • Ogata Toshiyasu
    Department of Cerebrovascular Disease, Cerebrovascular Center and Clinical Research Institute, National Hospital Organization Kyushu Medical Center
  • Yasaka Masahiro
    Department of Cerebrovascular Disease, Cerebrovascular Center and Clinical Research Institute, National Hospital Organization Kyushu Medical Center
  • Wakugawa Yoshiyuki
    Department of Cerebrovascular Disease, Cerebrovascular Center and Clinical Research Institute, National Hospital Organization Kyushu Medical Center
  • Kitazono Takanari
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
  • Okada Yasushi
    Department of Cerebrovascular Disease, Cerebrovascular Center and Clinical Research Institute, National Hospital Organization Kyushu Medical Center

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Other Title
  • 脳内出血患者における深部静脈血栓の発生部位とＤ－ｄｉｍｅｒ値の関連についての検討
  • ノウ ナイシュッケツ カンジャ ニ オケル シンブ ジョウミャク ケッセン ノ ハッセイ ブイ ト D-dimerチ ノ カンレン ニ ツイテ ノ ケントウ

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Aim: We investigated the association of the presence and the location of deep venous thrombosis (DVT) with D-dimer value in acute intracerebral hemorrhage (ICH).<br> Methods: We analyzed the data regarding DVT in patients with ICH. Based on an ultrasonographic examination 2 weeks after the occurrence of ICH, the patients were divided according to the presence/absence and the location of DVT, i.e. no evidence of DVT (n-DVT), calf DVT (c-DVT), and proximal DVT (p-DVT). D-dimer value was measured 2 weeks later and compared among the groups.<br> Results: The numbers of patients with n-DVT, c-DVT and p-DVT were 27, 19, and 2, respectively. Univariate analysis indicated that D-dimer values were significantly different between patients with n-DVT and c-DVT and between patients with n-DVT and p-DVT (p<0.05, respectively). The cut-off value for estimating the presence of DVT and p-DVT was 3.9 μg/mL and 18.5 μg/mL, respectively.<br> Conclusion: D-dimer value assessment after 2 weeks may be associated with the presence and the location of DVT in patients with ICH.<br>

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