Plasma Interleukin-6 in Patients with Disseminated Intravascular Coagulation

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  • MINAMIKAWA Kouzou
    2nd Department of Internal Medicine, Mie University School of Medicine
  • WADA Hideo
    2nd Department of Internal Medicine, Mie University School of Medicine
  • OHIWA Michiaki
    2nd Department of Internal Medicine, Mie University School of Medicine
  • KANEKO Toshihiro
    2nd Department of Internal Medicine, Mie University School of Medicine
  • TSUKADA Tetsuya
    2nd Department of Internal Medicine, Mie University School of Medicine
  • KAGEYAMA Sinichi
    2nd Department of Internal Medicine, Mie University School of Medicine
  • KOBAYASHI Tohru
    2nd Department of Internal Medicine, Mie University School of Medicine
  • TOMEOKU Makoto
    Department of Internal Medicine, Cyuusei General Hospital
  • KATOU Masami
    Department of Internal Medicine, Cyuusei General Hospital
  • MINAMI Nobuyuki
    Department of Blood Transfusion, Mie University School of Medicine
  • SHIRAKAWA Shigeru
    2nd Department of Internal Medicine, Mie University School of Medicine

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Other Title
  • 播種性血管内凝固症候群における血中IL-6値
  • ハシュセイ ケッカンナイ ギョウコ ショウコウグン ニ オケル ケッチュウ I

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Abstract

Plasma Interleukin-6 (IL-6) level was measured in 60 patients with disseminated intravascular coagulation (DIC). Plasma IL-6 level was high in patients with DIC, and was particularly high in patients with multiple organ failure (MOF) or poor prognosis. Plasma IL-6 level correlated positively with C-reactive protein in patients without DIC, but not in those with DIC. The increased plasma IL-6 level observed in DIC patients suggests that activation of the immune system is involved in the progression of DIC and in the pathology of organ failure.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 33 (12), 1797-1801, 1992

    The Japanese Society of Hematology

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