先端巨大症を合併し,VP療法にてひ腫と貧血が改善した特発性骨髄線維症

書誌事項

タイトル別名
  • Successful Treatment of Splenomegaly and Anemia by VP Therapy in Idiopathic Myelofibrosis Complicated with Acromegaly: A Case Report.
  • 先端巨大症を合併し,VP療法にて脾腫と貧血が改善した特発性骨髄線維症
  • センタン キョダイショウ オ ガッペイシ VP リョウホウ ニテ ヒ シュ ト

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抄録

Here we report a 65-year-old male patient with idiopathic myelofibrosis (IMF) accompanied with acromegaly. He was admitted because of anemia and splenomegaly. No favorable effects were observed when hydroyurea was administered. However, his symptoms were successfully treated by administration of vincristine and prednisolone (VP therapy), which is usually applied for choronic myelogenous leukemia in the accelerated phase. Therefore, VP therapy might be one possible for IMF. Since there have been several reports suggesting the possible association of hematological malignancies with acromegaly, we speculate that acromegaly was implicated in the initiation or progression of IMF in this case.

収録刊行物

  • 臨床血液

    臨床血液 36 (10), 1233-1236, 1995

    一般社団法人 日本血液学会

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